Dr Benedikt Ley
Senior research officer
PhD, University of Vienna, Austria, 2013; Master of Public Health, University of Liverpool, UK, 2011; Master of Science, University of Vienna, Austria, 2007
Benedikt Ley is a public health expert with a focus on diagnostics, Malaria and G6PD deficiency. He started his career in 2008 with the University of Vienna (Austria), based in Bangladesh working on infectious diseases in the Bangladesh / Myanmar border region.
He joined the International Vaccine Institute (Korea) based in Zanzibar and subsequently in Kenya focussing on typhoid fever. In 2012 Benedikt joined the Institute of Tropical Medicine, Antwerp (Belgium) where he worked on Salmonella spp. infections and in parallel completed his PhD in 2013 with the University of Vienna on the diagnosis of cholera and typhoid fever.
In 2014 Benedikt moved to Darwin, Australia, and joined the Menzies School of Health Research where he focuses on Malaria and G6PD deficiency. He is also a lecturer at the Charles Darwin University and coordinates the Vivax Working Group of the Asia Pacific Malaria Elimination Network (APMEN).
- ACROSS Study: Populations at risk of malaria and drug induced haemolysis
- IMPROV Study: Short-course treatment regimen for radical cure of P. vivax malaria
- Optimising the radical cure of vivax malaria (OPRA)
- PRIMA clinical trial: Universal Radical Cure of P. vivax malaria
- SIRIN clinical trial: Radical cure of P. vivax malaria in Nepal
- Asia-Pacific Malaria Elimination Project (APMEN).
- Ley, B., Khatib, A.M., Thriemer, K., von Seidlein, L., Deen, J., Mukhopadyay, A., et al.. (2012). Evaluation of a rapid dipstick (Crystal VC) for the diagnosis of cholera in Zanzibar and a comparison with previous studies. PloS one, 7(5), e36930. doi: 10.1371/journal.pone.0036930
- Ley, B., Le Hello, S., Lunguya, O., Lejon, V., Muyembe, J.J., Weill, F.X., & Jacobs, J. (2014). Invasive Salmonella enterica serotype typhimurium infections, Democratic Republic of the Congo, 2007-2011. Emerging Infectious Diseases, 20(4), 701-704. doi: 10.3201/eid2004.131488
- Ley, B., Mtove, G., Thriemer, K., Amos, B., von Seidlein, L., Hendriksen, I., et al. (2010). Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies. BMC Infectious Diseases, 10, 180. doi: 10.1186/1471-2334-10-180
- Ley, B., Thriemer, K., Ame, S.M., Mtove, G.M., von Seidlein, L., Amos, B., et al. (2011). Assessment and comparative analysis of a rapid diagnostic test (Tubex(R)) for the diagnosis of typhoid fever among hospitalized children in rural Tanzania. BMC Infectious Disease, 11, 147. doi: 10.1186/1471-2334-11-147
- Ley, B., Wernsdorfer, G., Frank, C., Sirichaisinthop, J., Congpuong, K., & Wernsdorfer, W.H. (2008). Pharmacodynamic interaction between 4-aminoquinolines and retinol in Plasmodium falciparum in vitro. Wien Klin Wochenschr, 120(19-20 Suppl 4), 74-79. doi: 10.1007/s00508-008-1079-1
- Thriemer, K., Ley, B., Ame, S.M., Puri, M.K., Hashim, R., Chang, N.Y., et al. (2012). Replacing paper data collection forms with electronic data entry in the field: findings from a study of community-acquired bloodstream infections in Pemba, Zanzibar. BMC Research Notes, 5, 113. doi: 10.1186/1756-0500-5-113
- Thriemer, K., Ley, B., Ame, S.S., Deen, J.L., Pak, G.D., Chang, N.Y., et al. (2012). Clinical and epidemiological features of typhoid fever in Pemba, Zanzibar: assessment of the performance of the WHO case definitions. PLoS One, 7(12), e51823. doi: 10.1371/journal.pone.0051823
- Thriemer, K., Ley, B., Ame, S., von Seidlein, L., Pak, G.D., Chang, N.Y., et al. (2012). The burden of invasive bacterial infections in Pemba, Zanzibar. PloS one, 7(2), e30350. doi: 10.1371/journal.pone.0030350
- Thriemer, K., Ley, B.B., Ame, S.S., Deen, J.L., Pak, G.D., Chang, N.Y., et al. (2012). Clinical and epidemiological features of typhoid fever in Pemba, Zanzibar: assessment of the performance of the WHO case definitions. PloS one, 7(12), e51823. doi: 10.1371/journal.pone.0051823
- Thriemer, K., Ley, B., Menten, J., Jacobs, J., & van den Ende, J. (2013). A systematic review and meta-analysis of the performance of two point of care typhoid fever tests, Tubex TF and Typhidot, in endemic countries. PLoS One, 8(12), e81263. doi: 10.1371/journal.pone.0081263
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Among the other projects funded are the Menzies School of Health Research partnering with Bangladesh, Indonesia and Nepal to develop malaria treatments.
The largest grant, of $257,767, goes to the Menzies School of Health Research for a project with collaborators in Bangladesh, Indonesia and the Netherlands.
MESA Correspondents bring you cutting-edge coverage from the 7th International Conference on Plasmodium vivax Research (ICPVR 2019).
A large clinical trial in Africa and Asia has shown that a 7 day course of high dose primaquine, a drug used to treat P. vivax malaria, is well tolerated.