Associate Professor Heidi Smith-Vaughan

Head of Child Health Laboratory Research and career development fellow

Qualifications:

PhD, University of Sydney, 2000; Bachelor of Science, Griffith University, 1989.

Approved level of HDR supervision at Charles Darwin University:

Principal Supervisor for PhD

Location:

Darwin - Royal Darwin Hospital campus

Biography:

Associate Professor Heidi Smith-Vaughan joined the Menzies School of Health Research in 1990 and was initially involved in chlamydia and melioidosis research, but for two decades her primary focus has been respiratory health.

She is head of Child Health Laboratory Research at Menzies and an National Health and Medical Research Council (NHMRC) Career Development Fellow. In these roles, she supervises laboratory research staff and students working on ear and respiratory research projects in the fields of Indigenous and international child health. She also engages in field work and research feedback and has a heavy involvement in youth engagement activities at Menzies.

Currently Assoc Prof Smith-Vaughan is an investigator on NHMRC and industry-funded clinical trials of the efficacy of vaccines and antibiotics for otitis media and suppurative lung disease in Indigenous children, and applies microbiological and molecular outcomes to these trials including microbiomics and whole genome sequencing. In the international arena, she has the role of microbiology coordinator of a pneumococcal vaccine trial in Vietnam.

In 2014, she was awarded the Ryan Family Prize, recognising her outstanding contributions to Menzies.

 
  • HOT NORTH - Improving Health Outcomes in the Tropical North: A Multidisciplinary Collaboration
  • HealthLAB project
  • MINOPOLI – microbes In the nasopharynx prior to lung infection (NHMRC, 2012-2014)
  • Molecular public health in Australian Indigenous communities and developing countries in our region to improve ear and respiratory outcomes (NHMRC Fellowship, 2012-2015)
  • Innovative measures of effect for innovative vaccination schedules (Northern Territory Research and Innovation Board, 2012-2014)
  • CHiRRP – combating H. influenzae related respiratory pathology (NHMRC, 2012-2014)
  • Is long term weekly azithromycin use for bronchiectasis in Indigenous children associated with antibiotic resistance? (NHMRC, 2009-2012)
  • Single versus combination pneumococcal conjugate vaccines (13PCV and PHiD-CV) for high-risk Aboriginal children (PREVIX_COMBO) (NHMRC, 2010-2013)
  • Cross sectional study of lower airway infection, nasopharyngeal carriage and adaptive immunity to NTHi in children immunized with Synflorix®. (GSK Biologicals, 2011-)
  • Can a pneumococcal H. influenzae protein D conjugate vaccine (PHiD-CV) reduce the frequency of NTHi infection in the lower airway and upper airway colonisation of children with CSLD? (Financial Markets for Children, 2011–)
  • Microbiology coordinator for a pneumococcal vaccine trial in Vietnam
  • Microbiology co-chair for pneumococcal vaccinology CRE (NHMRC, 2012-2016) 
  • Supervisor of students and staff involved in various other projects relating to oral microbiology, Vitamin D and pneumococcal epidemiology.
 
  1. Binks, M.J., Temple, B., Kirkham, L.-A.. Wiertsema, S.P., Dunne, E.M., Richmond, P.C., Marsh, R.L., Leach, A.J. & Smith-Vaughan, H.C. (2012). Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.  PLoS One, 7, e34083.
  2. Marsh, R.L., Beissbarth, J., Christensen, P., Binks, M.J., Morris, P.S., Leach, A.J. & Smith-Vaughan, H.C. (2012). Quantitative PCR of ear discharge from Indigenous Australian children with acute otitis media supports Alloiococcus otitidis as a secondary otopathogen. BMC Ear, Nose and Throat Disorders, 12, 11.
  3. Morris, P.S., Gadil, G., McCallum, G.B., Wilson, C.A., Smith-Vaughan, H.C., Torzillo, P., et al. (2010). Single-dose azithromycin versus seven days of amoxycillin in the treatment of acute otitis media in Aboriginal children (AATAAC): a double blind, randomised controlled trial. Medical Journal of Australia, 192(1), 24-29.
  4. Marsh, R., Smith-Vaughan, H., Hare, K.M., Binks, M., Kong, F., Warning, J., et al. (2010). The non-serotypeable pneumococcus: phenotypic dynamics in the era of anti-capsular vaccines. Journal of Clinical Microbiology, 48(3), 831-835.
  5. Leach, A.J., Morris, P.S., McCallum, G.B., Wilson, C.A., Stubbs, L., Beissbarth, J., Jacups, S., Hare, K. & Smith-Vaughan, H.C. (2001). Emerging pneumococcal carriage serotypes in a high-risk population receiving universal 7-valent pneumococcal conjugate vaccine and 23-valent polysaccharide vaccine since 2001. BMC Infectious Diseases, 9, 121.
  6. Smith-Vaughan H., Marsh, R., Mackenzie, G., Fisher, J., Morris P.S., Hare, K., et al. (2009). Age-Specific Cluster of Cases of Serotype 1 Streptococcus pneumoniae Carriage in Remote Indigenous Communities in Australia. Clinical and Vaccine Immunology, 16(2), 218-221.
  7. Smith-Vaughan, H.C., Byun, R., Halpin, S., Nadkarni. M., Jacques, N.A., Hunter, N., et al. (2008). Interventions for prevention of otitis media may be most effective if implemented in the first weeks of life. International Journal of Pediatric Otorhinolaryngology, 72(1), 57-61.
  8. Smith-Vaughan, H.C., Marsh, R.L., Morris, P.S., Leach, A.J. (2007). In vivo emergence of high-level macrolide resistance in Streptococcus pneumoniae following a single dose of azithromycin. Journal of Clinical Microbiology, 45(12), 4090-4091.
  9. Smith-Vaughan, H.C., Byun, R., Nadkarni, M., Jacques, N.A., Hunter, N., Halpin, S.. et al. (2006).  Measuring nasal bacterial load and its association with otitis media. BMC Ear, Nose and Throat Disorders, 6, 10.
  10. Smith-Vaughan, H.C., McBroom, J., Mathews, J.D. (2001).  Modelling of endemic carriage of Haemophilus influenzae in Aboriginal infants in Northern Australia.  FEMS Immunology and Medical Microbiology, 31(2), 137-143.
Click here to view more Heidi Smith-Vaughan publications in PubMed.
  1. Menzies School of Health Research home to three superstars of STEM

    Menzies School of Health Research home to three superstars of STEM

    Date

    Three Menzies School of Health Research researchers are among the new round of 2019 Superstars of STEM.

  2. HealthLAB in Australian Geographic

    HealthLAB in Australian Geographic

    Date

    Australian Geographic July - August 2018 promotes HealthLAB National Science Week event at NT Parliament House.

  3. Barunga cuts sugar for festival

    Barunga cuts sugar for festival

    Date

    Festival goers will also get the chance to find out more about the importance of good health and nutrition at the Menzies School of Health Research mobile HealthLAB during the Festival.

  4. Heart Foundation partnership with HealthLAB - NT News

    Heart Foundation partnership with HealthLAB - NT News

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    Heart Foundation partnership with HealthLAB - NT News report

  5. HealthLAB expands educational offering through Heart Foundation partnership

    HealthLAB expands educational offering through Heart Foundation partnership

    Date

    People living in remote NT communities will benefit from an expanded health education offering through a partnership between Menzies and the Heart Foundation.

  6. West Arnhem Wire | HealthLAB in Jabiru

    West Arnhem Wire | HealthLAB in Jabiru

    Date

    The Jabiru community is reminded that the Menzies HealthLAB will be at the Bowali Visitor Centre on Wednesday, August 16 as part of National Science Week 2017.

  7. NT News - Menzies HealthLAB at Parliament House

    NT News - Menzies HealthLAB at Parliament House

    Date

    HealthLAB in Parliament House for Science Week pollies health checks, NT Thunder captain Shannon Rioli calls on the general public to come along.

  8. Territory Q features HOT NORTH

    Territory Q features HOT NORTH

    Date

    Read about our HOT NORTH collaboration in the latest Territory Q Magazine.

  9. Menzies HealthLAB to visit Bowali Visitor Centre

    Menzies HealthLAB to visit Bowali Visitor Centre

    Date

    The Menzies HealthLAB will be at the Bowali Visitor Centre on Wednesday, August 16 as part of National Science Week 2017. Using the latest technology to measure participantsí health and inform them about the impacts of smoking, alcohol misuse and diet, which can increase the risk of diabetes, cancer, kidney disease, obesity and cardiovascular disease.

  10. Check-up gives health insight - HealthLAB

    Check-up gives health insight - HealthLAB

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    Darwin Sun | The Menzies School of Health and Research runs HealthLAB, a free initiative that visits public spaces and schools around the NT

  11. HOT NORTH Fellowships to improve health outcomes in the tropics

    HOT NORTH Fellowships to improve health outcomes in the tropics

    Date

    Five post-doctoral health professionals have been awarded Fellowships to help close critical gaps in health outcomes in northern Australia and the Asia-Pacific region as part of the unique collaborative program Improving Health Outcomes in the Tropical North (HOT NORTH), led by the Darwin-based Menzies School of Health Research (Menzies).

  12. Menzies HealthLAB National Science Week Grant

    Menzies HealthLAB National Science Week Grant

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    In August 2017, HealthLAB is planning to travel from the Tiwi Islands in the Arafura Sea across to west Arnhem Land.

  13. Health Lab promotes healthy living in the NT

    Health Lab promotes healthy living in the NT

    Date

    The Health Lab teaches Aboriginal children how to look after their health also look at ways to prevent chronic disease in Aboriginal communities through out the Northern Territory. Dietitian Claire Georga from the Menzies School of Health Researchers works with the kids to promote healthy living allowing them to test their heath to give them a better understanding of what is good for the body and what isnít.

  14. Lab teaches remote kids healthy living

    Lab teaches remote kids healthy living

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    IN a busy classroom on the Tiwi Islands, teacher's aide Stan blows into a breathalyser measuring carbon dioxide from smoke in the body, almost sending himself off the classroom scale. His students dissolve into laughter.WHEN asked, he sheepishly admits to smoking. "You play footy? You'll run faster if you quit," says a researcher from the Heart Foundation.