Associate Professor Matthew Grigg
Principal Research Fellow
Qualifications:
PhD, Charles Darwin University, 2017; Diploma of Tropical Medicine and Hygiene, Gorgas Memorial Institute, Peru, 2016; Bachelor of Medicine and Bachelor of Surgery, University of Melbourne, 2007; Bachelor of Medical Science, University of Melbourne, 2007.
Location:
Darwin - Royal Darwin Hospital; Sabah - Malaysia
Biography:
Matt is a NHMRC Emerging Leader II who has experience conducting and leading studies related to the epidemiology, diagnostics, and clinical drug trials of malaria and other tropical infectious diseases in Southeast Asia, with a focus on zoonotic malaria due to the monkey parasite Plasmodium knowlesi.
Matt also works as a clinician in Indigenous health in remote communities in East Arnhem Land.
Research Themes
- Parasite and human genetic risk factors for emerging Plasmodium knowlesi malaria
- ZOOMAL - Evaluating zoonotic malaria transmission and agricultural land use in Indonesia
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Grigg, M.J., William, T., Barber, B.E., Rajahram, G.S., Menon, J., Schimann, E., Piera, K.A., Wilkes, C.S., Patel, K., Chandna, A., Drakeley, C.J., Yeo, T.W., Anstey, N.M. (2018). Age-related clinical spectrum of Plasmodium knowlesi malaria and predictors of severity. Clinical Infectious Diseases. http://doi.10.1093/cid/ciy065. PMID: 29873683
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Grigg, M.J., William, T., Menon, J., Dhanaraj, P., Barber, B.E. & Wilkes, C.S. (2016). Artesunate–mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label randomised controlled trial. The Lancet Infectious Diseases, 16(2), 180-188. http://doi.org/10.1016/S1473-3099(15)00415-6. PMID: 26603174
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Grigg, M.J., Cox, J., William, T., Jelip, J., Fornace, K.M., Brock, P.M., von Seidlein, L., Barber, B.E., Anstey, N.M., Yeo, T.W. & Drakeley, C.J. (2017). Individual factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study. The Lancet Planetary Health, 1(3), e97-104. http://doi.org/S2542-5196(17)30031-1. PMID: 28758162
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Grigg, M.J., William, T., Barber, B.E., Rajahram, G.S., Menon, J., Schimann, E., Wilkes, C.S., Patel, K., Chandna, A., Price, R.N., Yeo, T.W. & Anstey, N.M. (2017). Artemether-lumefantrine versus chloroquine for the treatment of uncomplicated Plasmodium knowlesi malaria (CAN KNOW): an open-label randomized controlled trial. Clinical Infectious Diseases, 66(2), 229-232. http://doi.10.1093/cid/cix779. PMID: 29020373
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Grigg, M.J., William, T., Menon, J., Barber, B.E., Wilkes, C.S., Rajahram, G.S., Edstein, M.D., Auburn, S., Price, R.N., Yeo, T.W. & Anstey, N.M. (2016). Efficacy of artesunate-mefloquine against high-grade chloroquine-resistant Plasmodium vivax malaria in Malaysia: an open-label randomised controlled trial. Clinical Infectious Diseases, 62(11) 1403-11. http://doi.org/10.1093/cid/ciw121. PMID: 27107287
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Charon, J., Grigg, M.J., Eden, J.S., Piera, K.A., William, T., Rose, K., Davenport, M.P., Anstey, N.M. & Holmes, E.C. (2019). Matryoshka RNA virus 1: a novel RNA virus associated with Plasmodium parasites in human malaria. PloS Pathogens, 15(12). http://doi.10.1371/journal.ppat.1008216. PMID: 31887217
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Grigg, M.J. & Snounou, G. (2017). Plasmodium simium: a Brazilian focus of anthropozoonotic vivax malaria? The Lancet Global Health, 5(10), e961-962. http://doi.10.1016/S2214-109X(17)30343-1. PMID: 28867402
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Grigg, M.J., Barber, B.E., Marfurt, J., Imwong, M., William, T., Bird, E., Piera, K., Aziz, A., Boonyuen, U., Drakeley, C.J., Cox, J., White, N.J., Cheng, Q., Yeo, T.W., Auburn, S. & Anstey, N.M. (2016). Dihydrofolate-reductase mutations in Plasmodium knowlesi appear unrelated to selective drug pressure from putative human-to-human transmission in Sabah, Malaysia. PloS ONE, 11(3). http://doi.org/10.1371/journal.pone.0149519.t001. PMID: 26930493
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Piera, K.A., Aziz, A., William, T., Bell, D., González, I.J., Barber, B., Anstey, N.M. & Grigg, M.J. (2017). Detection of P. knowlesi, P. falciparum and P. vivax using loop-mediated isothermal amplification (LAMP) in a co-endemic area in Malaysia. Malaria Journal, 16(1), 29. http://doi.org/10.1186/s12936-016-1676-9. PMID: 28086789
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Grigg, M.J., William, T., Barber, B.E., Parameswaran, U., Bird, E., Piera, K., Aziz, A., Dhanaraj, P., Yeo, T.W. & Anstey, N.M. (2014). Combining parasite lactate dehydrogenase-based and histidine rich protein-2 rapid tests to improve specificity for the diagnosis of malaria due to Plasmodium knowlesi and other Plasmodium species in Sabah, Malaysia. Journal of Clinical Microbiology. http://doi.org/10.1128/JCM.00181-14. PMID: 24696029
Click here to view more Matthew Grigg publications in PubMed.