Associate Professor Anna Ralph
Senior clinical research fellow
PhD, Australian National University, 2010; Fellow of the Royal Australasian College of Physicians, 2005; Diploma of Hygiene and Tropical Medicine, University of London, 2002; Master of Public Health, University of Sydney, 1999; Bachelor of Medicine and Bachelor of Surgery Honours Class 1, University of New South Wales, 1996; Medical Science Honours Class 1, Australian National University, 1993; Bachelor of Medical Science, University of Tasmania, 1992.
Her research goals are to improve outcomes for people with diseases of poverty including tuberculosis and rheumatic fever. Her offshore research has included studies to improve knowledge of regional tuberculosis pathophysiology, epidemiology and treatment (in Indonesia and Malaysia). Her local research focus is on improving the management of acute rheumatic fever in the Northern Territory.
- The Tropical Disease Regional Research Regional Collaborative Initiative: Responding to Drug-Resistant Tuberculosis and Malaria in the Asia-Pacific
- Strengthening health systems to improve the delivery of tuberculosis contact investigation and preventive therapy in Timika (Indonesia) and Kota Kinabalu (Malaysia)
- Embedding sustained improvements in TB diagnosis and management into practice in eastern Malaysia
- Understanding the molecular epidemiology of TB in Sabah, Malaysia
- Improving the diagnosis of ARF
- Enhanced models of secondary prevention for RHD
- On Track Watch: a grassroots Rheumatic Heart Disease initiative in the Northern Territory
- Determinants and outcomes of adherence to secondary prophylaxis for ARF
- Improving delivery of secondary prophylaxis for rheumatic heart disease: a stepped-wedge, community-randomised trial (2012-2016).
- Ralph AP, Read C, Johnston V et al. (2016) Improving delivery of secondary prophylaxis for rheumatic heart disease in remote Indigenous communities: study protocol for a stepped-wedge randomised trial. Trials. 17:51.
- He V, Condon J, Ralph AP et al. (2016) Long-Term Outcomes from Acute Rheumatic Fever and Rheumatic Heart Disease: A Data-Linkage and Survival Analysis Approach. Circulation. 134:222-32.
- Davis JS, Sud A, O'Sullivan MV, Robinson JO, Ferguson PE, Foo H, van Hal SJ, Ralph AP, Howden BP, Binks PM, Kirby A, Tong SY (2016) Combination of vancomycin and β-lactam therapy for methicillin-resistant Staphylococcus aureus bacteremia: A pilot multicenter randomized controlled trial. Clin Infect Dis 62(2):173-80.
- Ralph AP, Waramori G, Pontororing GJ, et al. (2013) L-arginine and Vitamin D adjunctive therapies in pulmonary tuberculosis: a randomised, double-blind, placebo-controlled trial. PLoS ONE. (8):e70032.
- Ralph AP and Carapetis J. (2013) Group A streptococcal diseases and their global burden. Current Topics in Microbiology & Immunology. 368:1-27.
- Ralph AP, Lucas RM, Norval M. (2013) Vitamin D and solar ultraviolet radiation in the risk and treatment of tuberculosis. Lancet Infect Dis 13:77-88
- Ralph AP, Ardian M, Wiguna A et al. (2010) A simple, valid, numerical score for grading chest X-ray severity in adult smear positive pulmonary tuberculosis. Thorax, 65:863-869.
- Ralph AP, Yeo TW, Salome CM et al. (2013) Impaired Pulmonary Nitric Oxide Bioavailability in Pulmonary Tuberculosis: Association with Disease Severity and Delayed Mycobacterial Clearance with Treatment. JID, 204(4):616-26.
- Ralph AP, Fittock M, Schultz R et al. (2013) Improvement in rheumatic fever and rheumatic heart disease management and prevention using a health centre-based continuous quality improvement approach. BMC Health Serv Res.13:525.
- Ralph A, Jacups S, McGough K et al. (2006) The challenges of rheumatic fever diagnosis in a high-incidence population: A prospective study and proposed guidelines for diagnosis in Australia’s Northern Territory. Heart Lung Circ. 15(2):113-8.
Click here to view more Anna Ralph publications in PubMed.
The Northern Territory has the highest rate of rheumatic heart disease in the world, which is partly due to poor living conditions such as overcrowded housing, said Associate Professor Anna Ralph from the Menzies School of Health Research.
Work will begin to help close critical gaps in healthcare across northern Australia as the result of a $6m grant awarded today to Menzies School of Health Research (Menzies) by the National Health and Medical Research Council (NHMRC).
A $2m research grant to work towards the prevention, control and elimination of malaria and tuberculosis (TB) in Southeast Asia and the Pacific has been awarded to a consortium led by Menzies School of Health Research, in collaboration with Burnet Institute, the Department of Foreign Affairs and Trade announced today.
Australian researchers have uncovered a link between low levels of the gas nitric oxide in the lungs of tuberculosis patients and the bodyís ability to fight the deadly disease, opening the door to potential new treatments.
Journal of Infectious Diseases: Impaired Pulmonary Nitric Oxide Bioavailability in Pulmonary Tuberculosis
Impaired Pulmonary Nitric Oxide Bioavailability in Pulmonary Tuberculosis: Association with Disease Severity and Delayed Mycobacterial Clearance with Treatment.
New research from the Menzies School of Health Research could open the door to the development of new treatments for Tuberculosis (TB).
With a history as long as mankindís, TB lies dormant in one third of our global population.