Click here to view more malaria publications in PubMed.

Key publications in 2019

  1. Kho, S., Andries, B., Poespoprodjo, J.R., Commons, R.J., Shanti, P.A.I., Kenangalem E, Douglas NM, Simpson JA, Sugiarto P, Anstey N.M. ​​& ​Price, R.N. (2019). High risk of Plasmodium vivax malaria following splenectomy in Papua, Indonesia. Clinical Infectious Diseases, 68(1):51-60. doi: 10.1093/cid/ciy403.
  2. Commons, R.J., Simpson, J.A., Thriemer, K., Hossain, M.S., Douglas, N.M., Humphreys, G.S., Sibley, C.H., Guerin, P.J. & Price, R.N. (2019). The risk of Plasmodium vivax parasitaemia after P. falciparum infection: a systematic review and meta-analysis. Lancet Infectious Diseases, 19: 91-101. doi: 10.1016/S1473-3099(18)30596-6.
  3. Yeo, T.W., Weinberg, J.B., Lampah, D.A., Kenangalem, E., Bush, P., Chen, Y., Price,, R.N., Young, S., Zhang, H.Y., Millington, D., Granger, D.L. & Anstey, N.M. (2019). Glycocalyx Breakdown is Associated with Severe Disease and Fatal Outcome in Plasmodium falciparum Malaria. Clinical Infectious Diseases, 69(10): 1712-1720. doi: 10.1093/cid/ciz038.
  4. Kenangalem, E., Poespoprodjo, J.R., Douglas, N.M., Burdam, F.H., Gdeumana, K., Chalfein, F., Prayoga, Thio, F., Devine, A., Marfurt, J., Waramori, G., Yeung, S., Noviyanti, R., Penttinen, P., Bangs, M.J., Sugiarto, P., Simpson, J.A., Soenarto, Y., Anstey, N.M. &, Price, R.N. (2019). Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: a longitudinal surveillance study. PLoS Medicine 16(5): e1002815. doi: 10.1371/journal.pmed.1002815.
  5. Taylor, W.R.J., Thriemer, K., von Seidlein, L., Yuentrakul, P., Assawariyathipat, T., Assefa, A., Auburn, S., Chand, K., Chau, N.H., Cheah, P.Y. Dong, L.T., Dhorda, M., Degaga, T.S., Devine, A., Ekawati, L.L., Fahmi, F., Hailu, A., Hasanzai, M.A., Hien, T.T. ... Price, R.N. (2019). Short course primaquine for the radical cure of Plasmodium vivax malaria: a randomised placebo-controlled multicentre trial. The Lancet, 394: 929–38. doi: 10.1016/S0140-6736(19)31285-1.
  6. Commons, R.J., Simpson, J.A., Thriemer, K., Chu, C.S., Douglas, N.M., Abreha, T., Alemu, S.G., Anez, A., Anstey, N.M., Aseffa, A., Aseffa, A., Awab, G.R., Baird, J.K., Barber, B.E., Borghini-Fuhrer, I., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P.J., ... Price, R.N. (2019). The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. BMC Medicine, 17:151. doi: 10.1186/s12916-019-1386-6.
  7. Commons, R.J., Simpson, J.A., Thriemer, K., Abreha, T., Adam, I., Anstey, N.M., Assefa, A., Awab, G.R., Baird, J.K., Barber, B.E., Chu, C.S., Dahal, P., Daher, A., Davis, T.M.E., Dondorp, A.M., Grigg, M.J., Humphreys, G.S., Hwang, J., Karunajeewa, H., ... Price, R.N. (2019). The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: a systematic review and individual patient data meta-analysis. PLoS Medicine, 16(10): e1002928. doi: 10.1371/journal.pmed.1002928.
  8. Rajahram, G.S., Cooper, D.J., William, T., Grigg, M.J., Anstey, N.M. & Barber, B.E. (2019). Deaths from Plasmodium knowlesi malaria: case series and systematic review. Clinical Infectious Diseases, 69(10): 1703–1711. doi: 10.1093/cid/ciz011. 
  9. Cooper, D.J., Rajahram, G.S., William, T., Jelip, J., Mohammad, R., Benedict, J., Alaza, D.A., Malacova, E., Yeo, T.W., Grigg, M.J., Anstey, N.M. & Barber, B.E. (2020). Plasmodium knowlesi malaria in Sabah, Malaysia, 2015-2017: ongoing increase in incidence despite near-elimination of the human-only Plasmodium species. Clinical Infectious Diseases, 70(3): 361–367. doi: 10.1093/cid/ciz237.
  10. Kho, S., Minigo, G., Andries, B., Leonardo, L., Prayoga, P., Poespoprodjo, J.R., Kenangalem, E., Price, R.N., Woodberry, T., Anstey, N.M. & Yeo, T.W.. (2019). Circulating neutrophil extracellular traps and neutrophil activation are increased in proportion to disease severity in human malaria. The Journal of Infectious Diseases, 219(12): 1994–2004. doi: 10.1093/infdis/jiy661.
  11. Barber, B.E., Grigg, M.J., Piera, K., Amante, F.H., William, T., Boyle, M.J., Minigo, G., Dondorp, A.M., McCarthy, J.S. & Anstey, N.M. (2019). Antiphosphatidylserine IgM and IgG antibodies are higher in vivax than falciparum malaria, and associated with early anemia in both species. The Journal of Infectious Diseases, 220(9): 1435–1443. doi: 10.1093/infdis/jiz334.

Selected recent publications (2017-2020)

Clinical trials, meta-analyses and systematic reviews
  1. Abreha, T., Hwang, J., Thriemer, K., Tadesse, Y., Girma, S., Melaku, Z., Assefa, A., Kassa, M., Chatfield, M.D., Landman, K.Z., Chenet, S.M., Lucchi, N.W., Udhayakumar, V., Zhou, Z., Shi, Y.P., Kachur, S.P., Jima, D., Kebede, A., Solomon, H. ... Price, R.N. (2017). Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax in Ethiopia: a randomized controlled trial. PLoS Medicine, 14(5) e1002299. doi: 10.1371/journal.pmed.1002299.
  2. Grigg, M.J., William, T., Piera, K.A., Rajahram, G.S., Jelip, J., Aziz, A., Menon, J., Marfurt, J., Price, R.N., Auburn, S., Barber, B.E., Yeo, T.W.  & Anstey, N.M. (2017). Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: in vivo therapeutic efficacy and kelch13 molecular marker surveillance. Malaria Journal, 17(1):463. doi: 10.1186/s12936-018-2593-x.
  3. Commons, R.J., Simpson, J.A., Thriemer, K., Humphreys, G.S., Abreha, T., Alemu, S.G., Anez, A., Anstey, N.M, Awab, G.R., Baird, J.K., Barber, B.E., Borghini-Fuhrer, I., Chu, C.S., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P.J., Erhart, A, Gomes, M.S.M. ... & Price, R.N. (2018). The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis. Lancet Infectious Diseases, 18(9): 1025-1034. doi: 10.1016/S1473-3099(18)30348-7. 
  4. Grigg, M.J., William, T., Barber, B.E., Rajahram, G.S., Menon, J., Schimann, E., Wilkes, C.S., Patel, K., Chandna, A., Price, R.N., Yeo, T.W. & Anstey, N.M. (2018). Artemether-lumefantrine versus chloroquine for the treatment of uncomplicated Plasmodium knowlesi malaria: an open-label randomized controlled trial (CAN KNOW). Clinical Infectious Diseases, 66(2): 229-236. doi: 10.1093/cid/cix779.
  5. Commons, R.J., Simpson, J.A., Thriemer, K., Hossain, M.S., Douglas, N.M., Humphreys, G.S., Sibley, C.H., Guerin, P.J. & Price, R.N. (2019). The risk of Plasmodium vivax parasitaemia after P. falciparum infection: a systematic review and meta-analysis. Lancet Infectious Diseases, 19: 91-101. doi: 10.1016/S1473-3099(18)30596-6.
  6. Taylor, W.R.J., Thriemer, K., von Seidlein, L., Yuentrakul, P., Assawariyathipat, T., Assefa, A., Auburn, S., Chand, K., Chau, N.H., Cheah, P.Y. Dong, L.T., Dhorda, M., Degaga, T.S., Devine, A., Ekawati, L.L., Fahmi, F., Hailu, A., Hasanzai, M.A., Hien, T.T. ... Price, R.N. (2019). Short course primaquine for the radical cure of Plasmodium vivax malaria: a randomised placebo-controlled multicentre trial. The Lancet, 394: 929–38. doi: 10.1016/S0140-6736(19)31285-1.
  7. Commons, R.J., Simpson, J.A., Thriemer, K., Abreha, T., Adam, I., Anstey, N.M., Assefa, A., Awab, G.R., Baird, J.K., Barber, B.E., Chu, C.S., Dahal, P., Daher, A., Davis, T.M.E., Dondorp, A.M., Grigg, M.J., Humphreys, G.S., Hwang, J., Karunajeewa, H., ... Price, R.N. (2019). The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: a systematic review and individual patient data meta-analysis. PLoS Medicine, 16(10): e1002928. doi: 10.1371/journal.pmed.1002928. 
  8. Commons, R.J., Simpson, J.A., Thriemer, K., Chu, C.S., Douglas, N.M., Abreha, T., Alemu, S.G., Añez, A., Anstey, N.M., Aseffa, A., Aseffa, A., Awab, G.R., Baird, J.K., Barber, B.E., Borghini-Fuhrer, I., D'Alessandro, U., Dahal, P., Daher, A., de Vries, P.J., Erhart, A., ... Price, R.N. (2019). The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. BMC Medicine, 17:151. doi: 10.1186/s12916-019-1386-6
  9. Ahmed, R., Poespoprodjo, J.R., Syafruddin, D., Khairallah, C., Pace, C., Lukito, T., Maratina, S.S., Asih, P.B.S., Santana-Morales, M.A., Adams, E.R., Unwin, V.T., Williams, C.T., Chen, T., Smedley, J., Wang, D., Faragher, B., Price, R.N.& ter Kuile, F.O. (2019). Efficacy and safety of Intermittent preventive treatment (IPT), intermittent screening and treatment (IST) and single screening and treatment (SST) with dihydroartemisinin-piperaquine for the control of malaria in pregnancy in Indonesia: An open label cluster-randomized controlled trial. Lancet Infectious Diseases, 19 (9), 973-987. doi: 10.1016/S1473-3099(19)30156-2.
Clinical spectrum and diagnosis
  1. Grigg, M.J., William, T., Barber, B.E., Rajahram, G.S., Menon, J., Schimann, E., Piera, K., Wilkes, C.S., Patel, K., Chandna, A., Drakeley, C.J., Yeo, T.W. & Anstey, N.M. (2018). Age-related clinical spectrum of Plasmodium knowlesi malaria and predictors of severity. Clinical Infectious Diseases 67(3): 350-359. doi: 10.1093/cid/ciy065.
  2. Aung, N.M., Nyein, P.P., Htut, T.Y., Htet, Z.W., Kyi, T.T., Anstey, N.M, Kyi, M.M. & Hanson, J. (2018). Antibiotic Therapy in Adults with Malaria: High Rate of Clinically Significant Bacteremia in Hospitalized Adults Diagnosed with Falciparum Malaria. The American Journal of Tropical Medicine and Hygiene, 99(3): 688–696. doi:10.4269/ajtmh.18-0378. 
  3. Kho, S., Andries, B., Poespoprodjo, J.R., Commons, R.J., Shanti, P.A.I., [...], Anstey, N.M, Price, R.N. (2019). High risk of Plasmodium vivax malaria following splenectomy in Papua, Indonesia. Clinical Infectious Diseases, 68(1): 51-60. doi: 10.1093/cid/ciy403.
  4. Rajahram, G.S., Cooper, D.J., William, T., Grigg, M.J., Anstey, N.M. & Barber, B.E. (2019). Deaths from Plasmodium knowlesi malaria: case series and systematic review. Clinical Infectious Diseases, 69(10):1703–1711. doi:10.1093/cid/ciz011.
  5. Ley, B., Satyagraha, A.W., Rahmat, H., von Fricken, M.E., Douglas, N.M., Pfeffer, D.A., Espino, F.E., von Seidlein, L., Henriques, G., Oo, N.N., Menard, D., Parikh, S., Bancone, G., Karahalios, A. & Price RN.  (2019) Performance of the Accessbio/Carestart rapid diagnostic test for the detection of glucose 6 phosphate dehydrogenase deficiency: a systematic review and meta-analysis. PLoS Medicine, 16(12): e1002992. doi: 10.1371/journal.pmed.1002992

Epidemiology, surveillance and health economics 
  1. Grigg, M.J., Cox, J., William, T., Jelip, J., Fornace, K.M., Brock, P.M., von Seidlein, L., Barber, B.E., Anstey, N.M, Yeo, T.W. & Drakeley, C.J. (2017). Individual factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study. Lancet Planet Health, 1(3), e97–e104. doi: 10.1016/S2542-5196(17)30031-1.
  2. Trimarsanto, H., Benavente, E.D., Noviyanti, R., Utami, R.A.S., Getachew, S., Kim, J.Y., Goo, Y.K., Wangchuck, S., Liu, Y., Gao, Q., Dowd, S., Cheng, Q., Clark, T.G., Price, R.N. & Auburn, S. (2017). VivaxGEN: A Platform for Comparative Analysis of Short Tandem Repeat Genotyping Data in Plasmodium vivax Populations. PLoS Neglected Tropical Diseases, 11(3): e0005465. doi: 10.1371/journal.pntd.0005465.
  3. Devine, A., Parmiter, M., Chu, C.S., Bancone, G., Nosten, F., Price, R.N., Lubell, Y. & Yeung, S. (2017). Using G6PD Tests to Enable the Safe Treatment of Plasmodium vivax Infections with Primaquine on the Thai-Myanmar border: a Cost-Effectiveness Analysis. PLoS Neglected Tropical Diseases, 11(5):e0005602. doi: 10.1371/journal.pntd.0005602.
  4. Douglas, N.M., Poespoprodjo, J.R., Patriani, D., Malloy, M.J., Kenangalem, E., Sugiarto, P., Simpson, J.A., Soenarto, Y., Anstey, N.M. & Price, R.N. (2017). Unsupervised primaquine for the treatment of Plasmodium vivax malaria relapses in southern Papua: a hospital-based cohort study. PLoS Medicine, 14(8): e1002379. doi: 10.1371/journal.pmed.1002379. 
  5. Auburn, S., Benavente, E.D., Miotto, O., Pearson, R.D., Amato, R., Grigg, M.J., Barber, B.E., William, T., Handayuni, I., Marfurt, J., Trimarsanto, H., Noviyanti, R., Sriprawat, K., Nosten, F., Campino, S., Clark, T.G.,Anstey, N.M, Kwiatkowski, D.P. & Price, R.N. (2018). Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics. Nature Communications, 9(1): 2585. doi: 10.1038/s41467-018-04965-4. 
  6. Kenangalem, E., Poespoprodjo, J.R., Douglas, N.M., Burdam, F.H., Gdeumana, K., Chalfein, F., Prayoga, Thio, F., Devine, A., Marfurt, J., Waramori, G., Yeung, S., Noviyanti, R., Penttinen, P., Bangs, M.J., Sugiarto, P., Simpson, J.A., Soenarto, Y., Anstey, N.M. &, Price, R.N. (2019). Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: a longitudinal surveillance study. PLoS Medicine 16(5): e1002815. doi: 10.1371/journal.pmed.1002815.
  7. Auburn, S., Getachew, S., Pearson, R.D., Amato, R., Miotto, O., Trimarsanto, H., Zhu, S.J., Rumaseb, A., Marfurt, J., Noviyanti, R., Grigg, M.J., Barber, B., William, T., Goncalves, S.M., Drury, E., Sriprawat, K., Anstey, N.M., Nosten, F., Petros, B., ... & Price, R.N. (2019). Genomic analysis of Plasmodium vivax in southern Ethiopia reveals selective pressures in multiple parasite mechanisms. Journal of Infectious Diseases, 220:1738-49. doi: 10.1093/infdis/jiz016
  8. Devine, A., Pasaribu, A.P., Teferi, T., Pham, H.T., Awab, G.R., Contantia, F., Nguyen, T.N., Ngo, V.T., Tran, T.H., Hailu, A., Gilchrist, K., Green, J.A., Koh, G., Thriemer, K., Taylor, W.R.J., Day, N.P.J., Price, R.N. & Lubell, Y. (2019). Provider and household costs of Plasmodium vivax malaria episodes: a multicountry comparative analysis of primary trial data. Bulletin of WHO, 97(12):828–836. doi: 10.2471/BLT.18.226688 
  9. Cooper, D.J., Rajahram, G.S., William, T., Jelip, J., Mohammad, R., Benedict, J., Alaza, D.A., Malacova, E., Yeo, T.W., Grigg, M.J., Anstey, N.M & Barber, B.E. (2020). Plasmodium knowlesi malaria in Sabah, Malaysia, 2015-2017: ongoing increase in incidence despite near-elimination of the human-only Plasmodium species. Clinical Infectious Diseases, 70(3): 361–367. doi: 10.1093/cid/ciz237

Pathogenesis and immunology 
  1. Barber, B.E., Grigg, M.J., William, T., Piera, K.A., Boyle, M., Yeo, T.W. & Anstey, N.M. (2017). Effects of Aging on Parasite Biomass, Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Plasmodium knowlesi and Plasmodium falciparum Malaria. Journal Infectious Diseases, 215(12): 1908-1917. doi: 10.1093/infdis/jix193.
  2. Kho, S., Barber, B.E., Johar, E., Andries, B., Poespoprodjo, J.R., Kenangalem, E., Piera, K.A., Ehmann, A., Price, R.N., William, T., Woodberry, T., Foote, S., Minigo, G., Yeo, T.W., Grigg, Anstey, N.M. & McMorran, B. (2018). Platelets kill circulating parasites of all major Plasmodium species in human malaria. Blood, 132(12):1332-1344. doi:10.1182/blood-2018-05-849307.
  3. Oyong, D.A., Kenangalem, E., Poespoprodjo, J.R., Beeson, J.G., Anstey, N.M. Price, R.N. & Boyle, M.J. (2018). Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia. JCI Insight, 3(22): 124854. doi: 10.1172/jci.insight.124854.
  4. Barber, B.E., Grigg, M.J., Piera, K.A., William, T., Cooper, D.J., Plewes, K., Dondorp, A.M., Yeo, T.W. & Anstey, N.M. (2018). Intravascular haemolysis in severe Plasmodium knowlesi malaria: association with endothelial activation, microvascular dysfunction, and acute kidney injury. Emerging Microbes Infection, 7(1):106. doi: 10.1038/s41426-018-0105-2.
  5. Barber, B.E., Russell, B., Grigg, M.J., Zhang, R., William, T., Amir, A., Lau, Y.L., Chatfield, M.D., Dondorp, A.M. & Yeo, T.W. (2018). Reduced red blood cell deformability in Plasmodium knowlesi malaria. Blood Advances, 2(4): 433-443. doi: 10.1182/bloodadvances.2017013730.
  6. Kho, S., Minigo, G., Andries, B., Leonardo, L., Prayoga, P., Poespoprodjo, J.R., Kenangalem, E., Price, R.N., Woodberry, T., Anstey, N.M. & Yeo, T.W. (2019). Circulating neutrophil extracellular traps and neutrophil activation are increased in proportion to disease severity in human malaria. The Journal of Infectious Diseases, 219(12):1994–2004. doi:10.1093/infdis/jiy661.
  7. Yeo, T.W., Weinberg, J.B., Lampah, D.A., Kenangalem, E., Bush, P., Chen, Y., Price, R.N., Young, S., Zhang, H.Y., Millington, D., Granger, D.L. & Anstey, N.M. (2019). Glycocalyx Breakdown is Associated with Severe Disease and Fatal Outcome in Plasmodium falciparum Malaria. Clinical Infectious Diseases, 69(10): 1712–1720. doi:10.1093/cid/ciz038.
  8. Loughland, J.R., Woodberry, T., Boyle, M.J., Tipping, P.E., Piera, K.A., Amante, F.H., Kenangalem, E., Price, R.N., Engwerda, C.R., Anstey, N.M., McCarthy, J.S. & Minigo G. (2019) Plasmodium falciparum activates CD16+ dendritic cells to produce TNF and IL-10 in subpatent malaria. Journal of Infectious Diseases, 219(4): 660-671. doi: 10.1093/infdis/jiy555.
  9. Barber, B.E., Grigg, M.J., Piera, K., Amante, F.H., William, T., Boyle, M.J., Minigo, G., Dondorp, A.M., McCarthy, J.S. & Anstey, N.M. (2019). Anti-phosphatidylserine IgM and IgG antibodies are higher in vivax than falciparum malaria, and associated with early anemia in both species. Journal of Infectious Diseases, 220(9):1435–1443. doi:10.1093/infdis/jiz334.