Beth Temple

Epidemiologist

Qualifications:

Master of Science (Epidemiology), London School of Hygiene and Tropical Medicine, 2005; Bachelor of Arts (Honours, Biological Sciences), University of Oxford, 2003.

Location:

Queensland

Biography:

Beth joined Menzies in 2008. Currently she is the epidemiologist for a program of pneumococcal research in Vietnam, involving the Pasteur Institute of Ho Chi Minh City and the Murdoch Children's Research Institute, Melbourne. This program of research centres around two large pneumococcal vaccine trials among infants in Ho Chi Minh City, for which she is the trial manager. These trials aim to generate evidence to aid decision-making regarding pneumococcal vaccine introduction in developing countries.

The first trial provided a head-to-head comparison of the two pneumococcal vaccines, PCV10 and PCV13, and evaluated various different schedules of PCV10. 

The second trial evaluated reduced-dose (0+1 and 1+1) schedules designed to provide protection primarily through herd immunity. Results from this trial are currently being written up for publication.

Previously, Beth also contributed to the Women's and Children's Health Hub, part of the AusAID Health Knowledge Hubs initiative, and the twinning partnership between Menzies and the Timor-Leste Cabinet of Health Research and Development. Before coming to Menzies, Beth lived in Fiji, working for a pneumococcal research program and in Uganda, working on a multi-drug resistant TB study and an HIV cohort study.
 

 

  • The Vietnam Pneumococcal Project - Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (NHMRC and Bill & Melinda Gates Foundation)
  • The Vietnam Pneumococcal Trial II (VPT-II) - Trial of simplified pneumococcal vaccination in Vietnam II: the herd immunity approach (Bill & Melinda Gates Foundation)
 

 

  1. Nation ML, Manna S, Tran HP, Nguyen CD, Vy LTT, Uyen DY, Phuong TL, Dai VTT, Ortika BD, Wee-Hee AC, Beissbarth J, Hinds J, Bright K, Smith-Vaughan H, Nguyen TV, Mulholland K, Temple B, Satzke C. Impact of COVID-19 nonpharmaceutical interventions on pneumococcal carriage prevalence and density in Vietnam. Microbiol Spectr. 2023 Feb14;11(1):e0361522
  2. Smith-Vaughan H, Temple B, Dai VTT, Hoan PT, Thuy HNL, Phan TV, Bright K, Toan NT, Uyen DY, Nguyen CD, Beissbarth J, Ortika BD, Nation ML, Dunne EM, Hind J, Lai J, Satzke C, Huu TN, Mulholland K. Effect of different schedules of ten-valent pneumococcal conjugate vaccine on pneumococcal carriage in Vietnamese infants: results from a randomised controlled trial. Lancet Reg Health West Pac. 2022 Dec 3;32:100651
  3. Temple B, Tran HP, Dai VTT, Bright K, Uyen DY, Balloch A, Licciardi P, Nguyen CD, Satzke C, Smith-Vaughan H, Nguyen TV, Mulholland K. Simplified 0+1 and 1+1 pneumococcal vaccine schedules in Ho Chi Minh City, Vietnam: protocol for a randomised controlled trial. BMJ Open. 2021 Nov 29;11(11):e056505
  4. Higgins RA, Temple B, Dai VTT, Phan TV, Toan NT, Spry L, Toh ZQ, Nation ML, Ortika BD, Uyen DY, Cheung YB, Nguyen CD, Bright K, Hinds J, Balloch A, Smith-Vaughan H, Huu TN, Mulholland K, Satzke C, Licciardi PV. Immunogenicity and impact on nasopharyngeal carriage of a single dose of PCV10 given to Vietnamese children at 18 months of age. Lancet Reg Health West Pac. 2021 Sep 20;16:100273
  5. Temple B, Licciardi PV, Dai VTT, Toan NT, Uyen D, Nguyen CD, Phan TV, Bright K, Marimla RA, Balloch A, Huu TN, Mulholland K. Immunogenicity of alternative ten-valent pneumococcal conjugate vaccine schedules in infants in Ho Chi Minh City, Vietnam: results from a single-blind, parallel-group, open-label randomised, controlled trial. Lancet Infect Dis. 2021 Oct;21(10):1415-1428
  6. Temple B, Nation ML, Dai VTT, Beissbarth J, Bright K, Dunne EM, Hinds J, Hoan PT, Lai J, Nguyen CD, Ortika BD, Phan TV, Thuy HNL, Toan NT, Uyen DY, Satzke C, Smith-Vaughan H, Huu TN, Mulholland K. Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam. Vaccine. 2021 Apr 15;39(16):2303-2310
  7. Dai VTT, Beissbarth J, Thanh PV, Hoan PT, Thuy HNL, Huu TN, Bright K, Satzke C, Mulholland EK, Temple B, Smith-Vaughan HC. Hospital surveillance predicts community pneumococcal antibiotic resistance in Vietnam. J Antimicrob Chemother. 2020 Oct 1;75(10):2902-2906
  8. Temple B, Toan NT, Dai VTT, Bright K, Licciardi PV, Marimla RA, Nguyen CD, Uyen DY, Balloch A, Huu TN, Mulholland EK. Immunogenicity and reactogenicity of ten-valent versus 13-valent pneumococcal conjugate vaccines among infants in Ho Chi Minh City, Vietnam: a randomised controlled trial. Lancet Infect Dis. 2019 May;19(5):497-509
  9. Temple B, Toan NT, Uyen DY, Balloch A, Bright K, Cheung YB, Licciardi P, Nguyen CD, Phuong NTM, Satzke C, Smith-Vaughan H, Vu TQH, Huu TN, Mulholland EK. Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (The Vietnam Pneumococcal Project): protocol of a randomised controlled trial. BMJ Open. 2018 Jun 8;8(6):e019795
  10. Mulholland K and Temple B. Causes of death in children younger than 5 years in China in 2008 [letter]. Lancet 2010; 376(9735):89

Click here to view more Beth Temple publications in PubMed.

  1. Randomised controlled trial of the immunogenicity and reactogenicity of PCV10 versus PCV13 among infants in Ho Chi Minh City, Vietnam

    Randomised controlled trial of the immunogenicity and reactogenicity of PCV10 versus PCV13 among infants in Ho Chi Minh City, Vietnam